General Information

  • ID:  hor004181
  • Uniprot ID:  NA
  • Protein name:  Angiotensin I
  • Gene name:  NA
  • Organism:  Neoceratodus forsteri
  • Family:  Serpin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  NRVYVHPFTL
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Induced dose-dependent increases in arterial pressure
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004181_AF2.pdbhor004181_ESM.pdb

Physical Information

Mass: 140615 Formula: C59H88N16O14
Absent amino acids: ACDEGIKMQSW Common amino acids: V
pI: 9.35 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: 2 Boman Index: -1295
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 97
Instability Index: 1784 Extinction Coefficient cystines: 1490
Absorbance 280nm: 165.56

Literature

  • PubMed ID:  10208769
  • Title:  Teleost-type Angiotensin Is Present in Australian Lungfish, Neoceratodus Forsteri